| 1 | 184 | ME Trescothick | v Gloucestershire | County Ground, Taunton | 2008 | a19125 |
| 2 | 172* | ARI Umeed | v Derbyshire | The Incora County Ground, Derby | 2023 | a30168 |
| 3 | 151 | JC Hildreth | v Scotland | County Ground, Taunton | 2009 | a19793 |
| 4 | 175* | IT Botham | v Northamptonshire | Wellingborough School Ground, Wellingborough | 1986 | a4968 |
| 5 | 146* | JC Hildreth | v Durham | County Ground, Taunton | 2014 | a23427 |
| 6 | 108 | GA Bartlett | v Leicestershire | The Cooper Associates County Ground, Taunton | 2021 | a28516 |
| 7 | 165* | RE van der Merwe | v Surrey | The Cooper Associates County Ground, Taunton | 2017 | a25488 |
| 8 | 69* | C Kieswetter | v Glamorgan | County Ground, Taunton | 2007 | a18193 |
| 9 | 56 | BA Langford | v Glamorgan | Cardiff Arms Park, Cardiff | 1963 | a2 |
| 10 | 49* | AC Thomas | v Kent | County Ground, Taunton | 2014 | a23446 |
| 11 | 38* | KJ Shine | v Kent | Mote Park, Maidstone | 1996 | a9806 |