| 130 | ME Trescothick | England v West Indies | 2003/04 | a15854 |
| 124 | CH Gayle | West Indies v Pakistan | 2004/05 | a16645 |
| 108* | S Chanderpaul | West Indies v New Zealand | 2002 | a14337 |
| 106* | MN Samuels | West Indies v Pakistan | 2013 | a22726 |
| 103 | WW Cornwall | Antigua and Barbuda v Trinidad and Tobago | 2002/03 | a14465 |
| 103 | Mohammad Naim | Bangladesh A v West Indies A | 2022 | a29395 |
| 102 | Ahmed Shehzad | Pakistan v West Indies | 2011 | a21333 |
| 102 | KA Pollard | West Indies v Australia | 2011/12 | a21943 |
| 101 | L Vincent | New Zealand v Canada | 2006/07 | a18125 |