| 155 | MA Comber | Essex Second XI v Middlesex Second XI | The Ford County Ground, Chelmsford | set1961 |
| 135 | JRA Campbell | Unicorns A v Northamptonshire Second XI | Boughton Hall Avenue, Chester | set1978 |
| 133* | MW Machan | Sussex Second XI v Marylebone Cricket Club Young Cricketers | The PROBIZ County Ground, Hove | set2025 |
| 130 | AM Rossington | Middlesex Second XI v Essex Second XI | The Ford County Ground, Chelmsford | set1961 |
| 129 | GS Ballance | Yorkshire Second XI v Nottinghamshire Second XI | Headingley, Leeds | set1966 |
| 122* | MA Thornely | Unicorns A v Worcestershire Second XI | Marlins, Long Marston | set2006 |
| 120* | JS Gatting | Sussex Second XI v Surrey Second XI | Cricket Field Road, Horsham | set1988 |
| 118 | SP Terry | Marylebone Cricket Club Young Cricketers v Somerset Second XI | Willis Lane, North Perrott | set1958 |
| 118* | SJ Mullaney | Nottinghamshire Second XI v Unicorns A | Marlins, Long Marston | set2004 |
| 116 | TE Scollay | Middlesex Second XI v Glamorgan Second XI | Brunton Memorial Ground, Radlett | set2013 |
| 116* | AJ Blake | Kent Second XI v Gloucestershire Second XI | County Ground, Bristol | set2033 |
| 113 | RI Newton | Northamptonshire Second XI v Warwickshire Second XI | Stowe School Ground, Stowe | set1982 |
| 110 | SJ Walters | Glamorgan Second XI v Essex Second XI | The SWALEC Stadium, Cardiff | set2017 |
| 109 | J Clark | Lancashire Second XI v Worcestershire Second XI | Smithy Lane, Northop Hall | set1962 |
| 106 | AJ Blake | Kent Second XI v Marylebone Cricket Club Young Cricketers | The Kent County Cricket Ground, Beckenham | set1997 |
| 106* | CF Jackson | Sussex Second XI v Hampshire Second XI | The Rose Bowl (Nursery), Southampton | set2030 |
| 105 | MD Stoneman | Durham Second XI v Unicorns A | Brandon Lane, Brandon | set1984 |
| 101* | DJ Willey | Northamptonshire Second XI v Unicorns A | Boughton Hall Avenue, Chester | set1978 |
| 101 | K Turner | Nottinghamshire Second XI v Lancashire Second XI | Centre Vale, Todmorden | set2019 |